منابع مشابه
Towards DNA Sequencing Chips
DNA sequencing is an important technology for the determination of the sequences of nucleotides that make up a given DNA fragment. In view of the limitations of current sequencing technology, it would be advantageous to have a DNA sequencing method that provides the sequences of long DNA fragments and is amenable to automation. Sequencing by Hybridization (SBH) is a challenging alternative to t...
متن کاملProbe Design for DNA Chips
DNA chips are a promising fundamental technology for the post-genome research [1]. A large number of DNA oligonucleotide probes integrated in a small area of the chip surface facilitate speedy simultaneous detection of many target sequences. So, expression profile analysis of thousands of genes can be finished in a few days by using DNA chip technology although it takes years to finish the anal...
متن کاملSignal-amplifying conjugated polymer-DNA hybrid chips.
Bio-/synthetic hybrid materials have recently received considerable attention owing to their potential biomedical applications. The most reliable way of identifying any biological target is through its genetic code. However, the current commercial DNA microarray requires costly and time-consuming PCR to multiply the number of analyte DNA molecules and label the analyte DNA with a fluorescent dy...
متن کاملDNA Chips: from elaboration to application
The Nucleic Acids (DNA and RNA) are molecules holding the genetic information in all life cells and constitute the crucial and fundamental component of genes monitoring the working of living organisms. The scientific projects actually put in place through the world indicate clearly the strategic importance of the complete gene knowledge of wide varieties of live materials (Human Genomic Sequenc...
متن کاملNanowall Array Chips for Dna Separation
A 25 s separation of DNA fragments (48.5 and 1 kbp fragments) was achieved by a nanowall array structure, although the separation of 1 kbp and 100 bp DNA fragments was not. Direct observation of a single DNA molecule indicates that it takes over 20 s for an elongated DNA molecule to relax inside the nanowall array structure. Numerical fitting of DNA molecular dynamics reveals that the balance b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hyomen Kagaku
سال: 2003
ISSN: 0388-5321,1881-4743
DOI: 10.1380/jsssj.24.671